James Madison coach Bob Chesney looks up at the scoreboard during Saturday night's CFP loss to Oregon in Eugene.(AP photo)

EUGENE, Ore. (AP) — Dante Moore threw four touchdown passes and ran for another score and No. 5 Oregon beat No. 19 James Madison 51-34 on Saturday night in a College Football Playoff opener.

The game marked the end of Nashua North alum Curtis Harris-Lopez’ collegiate career. Harris-Lopez was a safety/special teamer with the Dukes.

The Ducks (12-1) advanced to face Texas Tech in a quarterfinal game at the Orange Bowl on Jan. 1. Oregon won a playoff game for the first time since 2014, when the Ducks beat Florida State in the Rose Bowl semifinal before losing to Ohio State.

James Madison (12-2) dropped Group of Five teams to 0-4 in CFP games. No. 17 Tulane fell 41-10 at No. 6 Mississippi as well Saturday.

Moore completed a 41-yard touchdown pass to Jamari Johnson less than two minutes into the game to give Oregon a lead it would not relinquish. Johnson hauled in Moore’s pass with his right hand, and romped into the end zone while dragging a pair of defenders.

James Madison responded with a 30-yard field goal from Morgan Suarez on its next drive, one which required 15 plays and burned 8:03. The Ducks took over from there, rattling off four straight touchdowns before the Dukes snuck in another field goal from Suarez ahead of halftime, which brought the score to 34-6.

In falling behind by such a wide margin, James Madison went away from its rushing attack, which ranked fifth in the nation in average yards per game entering the evening. Sun Belt Player of the Year Alonza Barnett III completed 23 of 48 passes, including a 47-yard touchdown pass to Nick DeGennaro on James Madison’s first drive of the third quarter.

Oregon promptly responded with two touchdowns, including wide receiver Malik Benson’s second TD and a blocked punt that Jayden Limar scooped and returned 15 yards for a score. James Madison scored the last three touchdowns.

The victory was the Ducks’ seventh straight since losing to No. 1 Indiana 30-20 on Oct. 11. James Madison had won 11 in a row.

MIAMI 10, TEXAS A&M 3

Miami brought a nasty defense into Texas A&M on Saturday to down the seventh-seeded Aggies in the College Football Playoff.

The No. 10 seed Hurricanes forced Marcel Reed into three turnovers and sacked him seven times in the victory.

“The defense was off the charts the entire day,” coach Mario Cristobal said.

They move on to face No. 2 Ohio State in the Cotton Bowl on New Year’s Eve.

Texas A&M had a chance to tie it after freshman Malachi Toney’s 11-yard touchdown reception with less than two minutes left.

The Aggies drove down the field and had a first down at the 5. But Miami (11-2) forced consecutive incompletions before fellow freshman Bryce Fitzgerald leapt in the end zone to grab his second interception of the day to secure the win.

OLE MISS 41, TULANE 10

New Mississippi coach Pete Golding spent the last minutes of his high-stakes debut taking in the smiling faces of his players on the sideline.

“To know what they’ve been through, and know the direction that they could have gone,” Golding said, alluding to coach Lane Kiffin’s departure for LSU. “They came here for some guys that looked like they left them, and they were able to battle through that. And for them to get the outcome that they deserve was awesome.”

Trinidad Chambliss ran for two touchdowns and passed for another, and No. 6 Mississippi looked unfazed by Kiffin’s absence, beating No. 17 Tulane in the first round of the College Football Playoff.

“The juice was there for sure,” Chambliss said. “We executed really well.”

Scoring runs of 20 yards by Kewan Lacy and 4 yards by Chambliss gave sixth-seeded Ole Miss (12-1) a 14-0 lead before eight minutes had elapsed, and 11th-seeded Tulane never got closer than 11 points after that.

Next up for Golding and sixth-seeded Ole Miss: a CFP quarterfinal against No. 2 Georgia in the Sugar Bowl on Jan. 1.

(Telegraph Staff Writer Tom King contributed to this report.)