Stephon Castle roars as he dunks against San Diego State in a Sweet 16 UConn blowout win Thursday night at TD Garden. (AP photo)

BOSTON (AP) — The rematch turned into another mismatch for UConn.

Stephon Castle had 16 points and 11 rebounds for the top-seeded Huskies and the defending NCAA champions advanced to the Elite Eight with another double-digit victory, beating San Diego State 82-52 on Thursday night in a rematch of last year’s title game.

Cam Spencer scored 18 points and Tristen Newton added 17 points and seven rebounds for the Huskies (34-3), who will play the winner of the other East Region semifinal between No. 2 Iowa State and No. 3 Illinois for a spot in the Final Four in Glendale, Arizona.

A year after cruising to their fifth national championship — winning their six NCAA Tournament games by an average of almost 20 points — the Huskies followed up blowouts last weekend with their ninth straight double-digit March Madness victory.

They have won their games in this tournament by 39, 17 and 30 points.

“We suck at winning close games,” UConn coach Dan Hurley said. “You’ve got to go with the alternative.”

Backed by a virtual home crowd at TD Garden — Boston is about 90 miles from UConn’s Storrs, Connecticut, campus — the Huskies made it a double-digit lead early in the second half, 20 with about seven minutes left and 30 in the final minutes, after the teams sent in their benches. Hurley’s son Andrew even got into the game with 1:44 left, drawing a celebratory cheer.

“We tried to make it like Storrs North,” Castle said. “They showed up for us.”

Seven-footer Donovan Clingan, who played just 23 minutes after getting into foul trouble, had eight points and eight rebounds.

Jaedon LeDee scored 15 of his 18 points in the first half for fifth-seeded San Diego State, which followed up the only Final Four appearance in school history with another Sweet 16 run.

But for the second straight year, the Aztecs (26-11) ran into UConn, which is now three victories away from becoming the first team to repeat as NCAA champions since Florida in 2006 and ’07.

UConn took its first 10-point lead before the midpoint of a first half in which both teams went cold about 10 minutes in. After opening a 27-16 lead with 11 minutes left, UConn shot 6 for 28 to finish the half — and still took a nine-point lead into the break.

The Huskies went up by double digits for good in the opening minutes of the second half when Newton — thanks to an offensive rebound and assist from Clingan — hit a 3-pointer to make it 45-33. Up 17 with eight minutes left, UConn scored the next nine points to pull away.

UConn won last year’s championship game 76-59 and also beat the Aztecs in the 2011 Sweet 16, with Kawhi Leonard’s San Diego State team falling to Kemba Walker’s Huskies, who went on to win the school’s third national championship.

Last year, UConn made it five, pulling away after leading by five points with five minutes left to beat San Diego State 76-59.

The Huskies reached the Elite Eight for the 13th time. The last time they made it this far and didn’t win it all was in 2009, when Jim Calhoun’s team lost to Michigan State in the national semifinal.

ILLINOIS 72, IOWA STATE 69

Terrence Shannon Jr. scored 29 points and Illinois reached the Elite Eight for the first time since 2005, beating Iowa State in the other East Region semifinal at TD Garden.

Shannon had 20 points in the first half for the third-seeded Illini (29-8), who never trailed. He broke away for a dunk in the closing seconds and later hit two free throws to help Illinois finally put away the second-seeded Cyclones (29-8).

Illinois made a regional final for the fourth time in the past 40 years and will meet defending champion UConn on Saturday for a trip to the Final Four. The top-seeded Huskies defeated San Diego State 82-52 in the earlier East semifinal.

Curtis Jones scored 26 points to lead Iowa State, which came into March Madness having blown out Houston for the Big 12 Tournament title.

WEST REGION

CLEMSON 77, NO. 2 ARIZONA 72

Chase Hunter scored 18 points and converted a three-point play with 25.7 seconds remaining, and Clemson advanced to the Elite Eight for the second time in school history, beating Arizona in Los Angeles.

PJ Hall added 17 points for the sixth-seeded Tigers (24-11), who advanced to face No. 4 seed Alabama.

Clemson last reached the final eight in 1980, when there were 48 teams in the NCAA Tournament. Coach Brad Brownell was making his second appearance in the second weekend of March Madness in his 14 seasons with the Tigers.

Oumar Ballo scored 15 points and Caleb Love 13 for second-seeded Arizona (27-9), which had a horrific shooting night, going 5 of 28 (17.9%) from 3-point range. Love missed all nine of his attempts beyond the arc as the Wildcats failed to reach the Elite Eight for the 12th time overall and first time since 2015.

NO. 4 ALABAMA 89, NO. 1 NORTH CAROLINA 87

Grant Nelson converted a go-ahead three-point play with 38 seconds remaining, and Alabama beat top-seeded North Carolina to reach the Elite Eight of the NCAA Tournament for the second time in school history.

Nelson finished with a season-high 24 points, 19 in the second half, and he blocked RJ Davis’ attempt at a tying layup after giving Alabama the lead. Rylan Griffen added 19 points, tying his career high with five 3-pointers, and Aaron Estrada also scored 19 for the fourth-seeded Crimson Tide (24-11).

The Tide face sixth-seeded Clemson on Saturday for a berth in the Final Four. The Tigers defeated second-seeded Arizona 77-72 in the first semifinal at Crypto.com Arena.

After Nelson blocked Davis’ shot with 25 seconds left, Davis furiously dribbled around before missing a layup and the Tar Heels got called for a shot-clock violation with 8 seconds left. They were forced to foul, sending Nelson to the line. He calmly made both for an 89-85 lead.

Armando Bacot scored inside with 1 second left, leaving North Carolina trailing 89-87. The Tar Heels fouled Nelson again with 0.9 seconds left. He missed both and time expired on the blueblood Tar Heels, who own six national championships.

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