North Carolina State's Cory Durden (48) celebrates a sack with teammate Khalid Martin (21) and Shyheim Battle (25) during the first half of Saturday's game against Clemson in Raleigh, (AP photo)

North Carolina State forced D.J. Uiagalelei into a fourth-down incompletion in the second overtime to beat ninth-ranked Clemson 27-21 on Saturday, an outcome that shakes up the Atlantic Coast Conference race and deals a huge blow to the Tigers’ College Football Playoff hopes.

Uiagagelei slightly overthrew Justyn Ross near the goal line to end it. Red-clad fans poured onto the field to celebrate N.C. State’s first win in the series in a decade.

Devin Leary threw for four touchdowns, including the winning 22-yard pass to Devin Carter to start the second OT.

N.C. State (3-1, 1-0 ACC) controlled play most of the way, nearly doubling Clemson in total offense through regulation while converting more than half of its third-down chances.

It was a brutal day for the Tigers (2-2, 1-1), who now have a second loss to make it an unlikely climb to make the playoff.

NO. 1 ALABAMA 63, SOUTHERN MISSISSIPPI 14

Jameson Williams opened the game with a 100-yard kickoff return, then added an 81-yard touchdown catch and another 83-yard runback in Alabama’s rout.

Williams and the Crimson Tide (4-0) needed just 14 seconds to put to rest any worries of a letdown against Southern Miss (1-3) after a close win over No. 11 Florida and with No. 13 Mississippi on deck. Bryce Young was nearly flawless in throwing for five touchdowns while completing 20 of 22 passes for 313 yards.

NO. 2 GEORGIA 62, VANDERBILT 0

JT Daniels threw for 121 yards and two touchdowns while playing only the first quarter as Georgia posted its biggest win in a series that started in 1893.

The game was effectively over when Georgia (4-0, 2-0 Southeastern Conference) led 35-0 after the first quarter. The Bulldogs started three of four drives in Vandy territory. They recovered a fumble on a kickoff to set up one TD, then Christopher Smith intercepted a pass to set up a second TD less than 30 seconds later.

NO. 4 OKLAHOMA 16, WEST VIRGINA 13

Gabe Brkic’s 30-yard field goal as time expired lifted Oklahoma over West Virginia.

Oklahoma started its final possession at its 8-yard line with 3:39 remaining. Quarterback Spencer Rattler completed all six of his passes for 54 yards on the final drive to get the Sooners into scoring range. The final drive was 14 plays and 80 yards.

Rattler passed for 256 yards and a touchdown. Mike Woods caught eight passes for 86 yards for the Sooners (4-0, 1-0 Big 12), who won their third game by seven or fewer points this season.

NO. 5 IOWA 24, COLORADO STATE 14

Spencer Petras threw for 224 yards and two touchdowns as the Hawkeyes needed a second-half comeback to stay unbeaten.

The Hawkeyes (4-0) won their 10th consecutive game and have a 15-game nonconference winning streak, the longest current streak in the nation.

Colorado State (1-3) led 14-7 at halftime, but the Hawkeyes scored touchdowns on back-to-back possessions that took a combined four plays in the third quarter.

NO. 6 PENN STATE 38, VILLANOVA 17

Sean Clifford passed for four touchdowns and a career-high 401 yards as Penn State showcased its speed against its in-state FCS opponent.

Clifford completed 19 of 26 passes, finding Parker Washington for two TDs and Jahan Dotson and KeAndre Lambert-Smith for one apiece. Tyler Warren rushed for a touchdown and Jordan Stout kicked a field goal for the Nittany Lions (4-0), who led 17-3 at the break in their eighth straight win.

NO. 10 OHIO STATE 59, AKRON 7

True freshman quarterback Kyle McCord overcame early jitters to throw for 319 yards and two touchdowns, freshman TreVeyon Henderson ran for 93 yards and two scores in the first half, and Ohio State routed Akron.

McCord got the nod in place of C.J. Stroud, a freshman who started the first three games but has a sore shoulder and got a breather against the seven-touchdown underdog. McCord was 13 for 18.

Master Teague III rushed for two second-half touchdowns, and Evan Pryor added another one late for Ohio State (3-1, 1-0 Big Ten).

NO. 11 FLORIDA 38, TENNESSEE 14

Emory Jones had two touchdown passes to go with a career-high 144 yards rushing, extending Florida’s nearly two decades of dominance in the series.

The Gators (3-1, 1-1 Southeastern Conference) won their fifth straight and 16th in 17 years in a series that used to go a long way toward deciding the Eastern Division.

NO. 12 NOTRE DAME 41, NO. 18 WISCONSIN 13

Chris Tyree returned a kickoff 96 yards for a touchdown and Drew Pyne threw a touchdown pass in the fourth quarter in relief of an injured Jack Coan to pace the Irish.

Brian Kelly became the winningest coach in Notre Dame history with victory No. 105, surpassing Knute Rockne in his 12th season with the Irish (4-0).

Graham Mertz threw four interceptions for Wisconsin (1-2), including two that were returned for touchdowns in the final 2:30 to blow the game open.

NO. 24 UCLA 35, STANFORD 24

Dorian Thompson-Robinson threw two touchdown passes in the fourth quarter and also ran for two short scores as the Bruins spoiled Stanford’s first home game after seven straight on the road.

Stanford (2-2, 1-1 Pac-12) had played its last seven games away from home because of COVID-19 protocols last season and a tough opening schedule. The Cardinal managed to win six of those games but came out flat against the Bruins (3-1, 1-0).

NEW ENGLAND

BOSTON COLLEGE 41,MISSOURI 34 (OT)

Denis Grosel threw a 10-yard touchdown pass to Zay Flowers in overtime, and Brandon Sebastian’s interception sealed the victory

BC coach Jeff Hafley said he couldn’t see Sebastian come down with the ball to end the game. But he figured it out when the fans came streaming onto the field to celebrate the first-ever meeting between the schools, and the Eagles’ first 4-0 start since Matt Ryan led them to eight straight wins to start the 2007 season.

“The next thing I know I had like 5,000 people on my back,” Hafley said. “It was a blur.”

Travis Levy scored from 5-yards out to give BC a 34-31 lead with 25 seconds to play in the fourth, bouncing off one defender at the 1 and scampering in. But Connor Bazelak led the Tigers (2-2) to the Eagles’ 39 and Harrison Mevis barely cleared the crossbar with a 56-yard field goal as time expired in regulation.

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