AP photo Oklahoma quarterback Spencer Rattler (7) carries against Missouri State defenders Ferrin Manulelua (5), Michael Pope (97), and Von Young (54) in the first half of OU's win Saturday night.

Here are some highlights from a full day and night Saturday of college football:

—Spencer Rattler threw for 290 yards and four touchdowns in his first start and No. 5 Oklahoma rolled past Missouri State 48-0 on Saturday night.

Rattler, the highly touted redshirt freshman from Phoenix, only played the first two quarters and helped the Sooners take a 41-0 lead.

The Sooners led 31-0 at the end of the first quarter and outgained the Bears 236 yards to 1. It was the first time since 2008 that Oklahoma scored at least 31 points in a first quarter and the sixth time in school history.

–Kyren Williams was ready to go in his starting debut at running back for Notre Dame. The No. 10 Irish rode the sophomore’s big day to a 27-13 victory over Duke on Saturday at rainy Notre Dame Stadium in the season and Atlantic Coast Conference opener for both teams.

“I’ve been getting a lot of reps,” Williams, who ran for 112 yards and two touchdowns in his first start on 19 carries and also was Notre Dame’s leading receiver with two receptions totaling 93 yards, one a 75-yarder in the first half on a screen play. “It took a couple of drives for me to finally relax and breathe.”

–Jonathan Adams Jr., Arkansas State, caught a career-high three TD passes, including the winner with 38 seconds remaining, and the Red Wolves beat Kansas State 35-31 for their first win over a Power 5 opponent in a dozen years.

–Kenny Pickett, Pittsburgh, threw a for 277 yards and TD and ran for another as the Panthers raced to a 55-0 victory over Austin Peay.

–Javonte Williams, North Carolina, ran for three fourth-quarter TDs and the No. 18 Tar Heels overcame a mistake-filled performance to beat Syracuse 31-6.

–Jarrett Doege, West Virginia, threw for 228 yards and three TDs in one half to help the Mountaineers beat Eastern Kentucky 56-10.

–Frank Harris, UTSA, accounted for four TDS and the Roadrunners won their season opener, beating Texas State 51-48 in a wild finish.

–Tyler Vitt, Texas State, threw for 346 yards and four TDs in a 51-48 loss to UTSA.

CAJUNS RAGIN

Perseverance, confidence and two long kick returns propelled Louisiana-Lafayette to one of its biggest wins in program history, 31-14 win over No. 23 Iowa State.

The Ragin’ Cajuns beat a Top 25 opponent on the road for the first time, having gone 0-26 against ranked foes away from home. Their only other win over a Top 25 team was in 1996 at home against Texas A&M.

Both offenses seemed overmatched at times, but the Ragin’ Cajuns were ignited by Chris Smith’s 95-yard kickoff return in the second quarter and Eric Garror’s 83-yard punt return in the fourth.

Levi Lewis added a 78-yard touchdown pass to Peter LeBlanc, giving Louisiana-Lafayette a 17-14 lead late in the third quarter.

Lewis passed for 154 yards and contributed to a business-like approach by the Ragin’ Cajuns, who didn’t celebrate much on the field after the game.

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Big Ten university presidents will meet Sunday to hear a presentation about playing a fall football season after all — maybe as soon as late October — amid pressure to kick off from parents, players, coaches and even the president.

A person with direct knowledge of the situation told The Associated Press the Big Ten’s Return to Competition Task Force met Saturday. The medical subcommittee, comprised of athletic directors, doctors and athletic training staffers, made a presentation to a subgroup of presidents and chancellors. The presentation included improvements in the availability of rapid, daily COVID-19 testing.